CAMP® Enabled Technology

(Continous Adaptive Multi Parameter)

Autologous cell therapy manufacturing demands consistent, high-quality cell outputs—yet traditional manual processes are labor-intensive, static, and provide limited insight into real-time cellular behavior. With only intermittent measurements and minimal in-process control, these systems cannot adapt to donor variability, often compromising performance.

Adva-X3 changes that.

Powered by CAMP® (Continuous Adaptive Multi-Parameter) Technology, Adva-X3 delivers a smart, simple, flexible, and cost-effective approach to cell manufacturing—unlike any other automation platform.

A Fully Integrated, Adaptive Cell Manufacturing Platform

The Adva-X3 enables a fully automated, end-to-end cell culture process within a single, closed chamber—from activation and transduction through high-density expansion.

By combining real-time metabolic sensing with advanced machine learning and AI, the system continuously learns each donor’s cellular behavior and dynamically adapts culture conditions to maximize cell quality and yield.

With continuous monitoring and control of 14 critical parameters, Adva-X3 ensures optimal conditions are maintained throughout the entire process—with minimal operator involvement.

The way it works:

Betch Mode

The proprietary Cone culture chamber is designed for early-stage processing,

including seeding, recovery, activation, and transduction.

• Embedded sensors measure conditions directly at the cell level
• Continuous control of pH, dissolved oxygen, and temperature
• Programmable automation for media handling and cell washing
• Closed, sterile connections for sampling and supplementation

Shearless Flow

A proprietary structured membrane guides media in a bottom-to-top flow,

creating a gentle, shear-free diffusion environment.

By replicating the body’s natural nutrient dynamics, it enables cells to grow

under truly optimal, physiologically relevant conditions.

Cell Expansion

A dedicated Media Conditioning Chamber continuously optimizes culture

conditions, including:

• pH, dissolved oxygen, glucose, lactate, glutamine, glutamate,

        and temperature

• Adaptive perfusion based on real-time cellular consumption
• Continuous media circulation for efficient nutrient utilization

This adaptive control enables each donor’s cells to reach their full

growth potential.

Media Change

transitions to Media Change Mode:

• Spent media is removed while fresh media is introduced
• Continuous perfusion ensures uninterrupted optimal conditions
• Fully programmable based on process requirements

Cell Wash & Harvest

At the final stage, cells are washed and prepared for harvest—without centrifugation:

• Gentle, programmable washing tailored to cell type
• Automated formulation and volume control
• Fast, efficient harvest in minutes to preserve high viability

Smarter Cell Manufacturing Starts Here

Adva-X3 combines automation, real-time insight, and adaptive intelligence to deliver consistent, high-quality results—while reducing complexity, labor, and cost.